Phosphatidyl-Serine-Positive Cells with High Sensitivity to the Alzheimer's Disease Aβ Peptides Display Distinctive Mitochondrial Characteristics

Puzzling Peptides from a Phage Display Library

The commercial availability of random peptide libraries displayed on the M13 phage is increasing their use forstudies on epitope identification, enzyme inhibitors, receptor ligands, etc. In this study two experimentswhere planned for selection of peptides. First with sheep antibodies, the positive selector was IgG, preparedon Protein G column from a pool of 11 sheeps immunized...

Phosphatidyl serine and phosphatidic acid complex (PSPATM)

Environmental monitoring of display cases in museums to consider the impact of display cases characteristics on their inner air quality

While technical characteristics, such as material used in the construction of display cases and their dimensions are important factors in terms of presentation quality as well as attracting the attention of the visitors, they can influence the inner air quality of the display case and preservation conditions of the exhibits too. This study intends to examine the effect of the technical characte...

16. Role of Phosphatidyl Serine in the Opiate Receptor*

The molecular nature and configuration of the opiate receptor is a problem under intensive investigation in a number of laboratories (1,2,3). Our interest in the problem developed as a result of a finding of others (4) that a proteolipid fraction from brain may be responsible for stereospecific opiate binding observed in various preparations of brain tissue. Upon examining various lipids, prote...

Locus coeruleus, norepinephrine and Aβ peptides in Alzheimer's disease

Monoaminergic brainstem systems have widespread projections that participate in many central processes and, when dysregulated, contribute to a plethora of neuropsychiatric and neurodegenerative disorders. Synapses are the foundation of these neuronal circuits, and their local dysfunction results in global aberrations leading to pathophysiological disease states. This review focuses on the locus...